Formulation and optimization of temozolomide nanoparticles by 3 factor 2 level factorial design

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Formulation and optimization of temozolomide nanoparticles by 3 factor 2 level factorial design

The aim of this study was to investigate the combined influence of 3 independent variables in the preparation of temozolomide bearing Non-PEGylated and PEGylated nanoparticles by emulsification solvent evaporation method. A 3 factor 2 level design was used to derive a polynomial quadratic model and construct contour plots to predict responses. The independent variables selected were concentrati...

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formulation of topical bioadhesive gel of aceclofenac using 3-level factorial design

the objective of this work was to develop bioadhesive topical gel of aceclofenac with the help of response-surface approach. experiments were performed according to a 3-level factorial design to evaluate the effects of two independent variables [amount of poloxamer 407 (pl-407 = x1) and hydroxypropylmethyl cellulose k100 m (hpmc = x2)] on the bioadhesive character of gel, rheological property o...

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Formulation of Topical Bioadhesive Gel of Aceclofenac Using 3-Level Factorial Design

The objective of this work was to develop bioadhesive topical gel of Aceclofenac with the help of response-surface approach. Experiments were performed according to a 3-level factorial design to evaluate the effects of two independent variables [amount of Poloxamer 407 (PL-407 = X1) and hydroxypropylmethyl cellulose K100 M (HPMC = X2)] on the bioadhesive character of gel, rheological property o...

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ژورنال

عنوان ژورنال: Biomatter

سال: 2013

ISSN: 2159-2535

DOI: 10.4161/biom.25102